Griffith University’s Sustainable Development Goal (SDG) initiative is transforming newborn care in rural Nepal by empowering frontline health workers to save lives from the very first breath. Addressing SDG 3 (Good Health and Well-being) the project confronts a pressing challenge: the loss of critical newborn resuscitation skills in remote settings, where access to refresher training is rare and clinical exposure is limited. To bridge this gap, the initiative adapted a mobile, simulation-based training tool developed in Uganda, working with the original development team, who are now part of the project team. The tool enables birth attendants to independently refresh their life-saving skills through culturally tailored, on-demand microlearning. Developed in close collaboration with local stakeholders, it is fully adapted to the Nepali language, clinical context, and cultural norms. The project is anchored by strong Nepali partnerships, including local NGOs, clinicians, and academic collaborators. Endorsed and actively supported by the Ministry of Health in Lumbini Province, it aligns closely with national health priorities and systems. Griffith University has demonstrated a deep and sustained institutional commitment to the initiative, providing leadership, academic oversight, and long-term support. This reflects the university’s broader dedication to advancing SDG 3 through high-impact global health partnerships that translate research into real-world change. Piloted successfully in underserved regions of Nepal, the approach has led to statistically significant improvements in knowledge retention and clinical performance. It stands as a powerful example of how universities can work alongside communities to drive equitable, lasting improvements in maternal and newborn health.